Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence
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چکیده
منابع مشابه
Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence.
OBJECTIVE The role of telomerase activity and telomere length in the adenoma-carcinoma sequence of colon carcinogenesis has not been well established. The objective of this study was to determine telomerase activity and telomere length patterns in patients with adenomatous polyps either associated or not with colorectal cancer, as well as the role of telomeric instability in the adenoma-carcino...
متن کاملTelomerase activity and telomere length in the colorectal polyp-carcinoma sequence
Objective: the role of telomerase activity and telomere length in the adenoma-carcinoma sequence of colon carcinogenesis has not been well established. The objective of this study was to determine telomerase activity and telomere length patterns in patients with adenomatous polyps either associated or not with colorectal cancer, as well as the role of telomeric instability in the adenoma-
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introduction: the telomeric dna together with its associated proteins protects the chromosome ends from degradation or aberrant recombination. telomerase and telomere are closely associated with development of cancers. in this study we aim to investigate the significance of telomerase activity (ta) and telomere length (tl) in patients with acute promyelocytic leukemia (apl). methods: peripher...
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Telomeres, comprised of short repetitive sequences, are essential for genome stability and have been studied in relation to cellular senescence and aging. Telomerase, the enzyme that adds telomeric repeats to chromosome ends, is essential for maintaining the overall telomere length. A lack of telomerase activity in mammalian somatic cells results in progressive shortening of telomeres with each...
متن کاملThe effect of high intensity interval training on telomere length and telomerase activity in non-athlete young men
Introduction: Telomeres are DNA portions that are located on the two ends of the chromosome. Telomeres play an important role in cellular life. Exercise is one of the factors that contributes to their control. The purpose of the present study was to investigate the effect of 8 weeks of high intensity interval training (HIIT) on telomere length and telomerase activity in non-athletic young men. ...
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ژورنال
عنوان ژورنال: Revista Española de Enfermedades Digestivas
سال: 2009
ISSN: 1130-0108
DOI: 10.4321/s1130-01082009000300004